In a medium-sized bowl, combine the yellow cornmeal and all-purpose flour.
Add the paprika, garlic powder, onion powder, salt, black pepper, and cayenne pepper (if using).
Whisk all ingredients together until thoroughly mixed.
Transfer the seasoning mix to an airtight container for storage.
To use, dredge your fish fillets in the seasoning mix, ensuring an even coating. Fry the coated fish in hot oil until golden brown and crispy.